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CD223 (Lag-3) Mouse anti-Human, eFluor 450, Clone: 3DS223H, eBioscience™

Mouse Monoclonal Antibody

$216.05 - $520.55

Specifications

Antigen CD223 (Lag-3)
Clone 3DS223H
Host Species Mouse
Gene Alias Lymphocyte Activation Gene-3
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501124149

 
affymetrix
48223942
100 tests Each for $520.55

501129290

 
affymetrix
48-2239-41
25 tests Each for $216.05
Description & Specifications

Specifications

Antigen CD223 (Lag-3)
Clone 3DS223H
Host Species Mouse
Gene Alias Lymphocyte Activation Gene-3
Species Reactivity Human
Applications Flow Cytometry
Regulatory Status RUO
Conjugate eFluor 450
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.125μg)/test

This 3DS223H monoclonal antibody recognizes human CD223 also known as Lymphocyte Activation Gene 3 (LAG-3). LAG-3 is a 70kDa surface glycoprotein belonging to the Ig superfamily with homology to CD4. LAG-3 binds to MHC class II with higher affinity than CD4 and is thought to be involved in the negative regulation of T cell activation and homeostatic proliferation. Surface expression of LAG-3 has been reported on activated T cells (including regulatory T cells) and NK cells. CD8+ T cells usually express LAG-3 at significantly higher levels than CD4+ T cells. Coexpression of LAG-3 and CD49b has been proposed to identify human and mouse Type 1 regulatory T cells (Tr1 cells).

This 3DS223H antibody will recognize a formaldehyde-fixed epitope.