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CD221 (Insulin-like Growth Factor-1 Receptor) Mouse anti-Human, Alexa Fluor 488, Clone: 1H7, eBioscience™

Mouse Monoclonal Antibody

$157.08 - $341.88

Specifications

Antigen CD221 (Insulin-like Growth Factor-1 Receptor)
Clone 1H7
Host Species Murine
Gene Alias IGF1R
Applications Flow Cytometry
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
50246091 Life Technologies
LS53884941
25 Tests Each for $157.08
50246092 Life Technologies
LS53884942
100 Tests Each for $341.88
Specifications

Description

This 1H7 monoclonal antibody reacts with human insulin-like growth factor-1 receptor (IGF-1R), also known as CD221. This receptor is a cell surface-expressed glycoprotein composed of two extracellular alpha subunits and two transmembrane beta subunits that possess tyrosine kinase activity. Expressed on nearly all cell types, this receptor binds IGF-I and IGF-II, as well as insulin. Ligand binding leads to activation of the PI3K/Akt and MAPK pathways, which mediate cell proliferation and survival. Many tumors and transformed cells display altered IGF-1R expression.

This monoclonal antibody has been reported to block binding of IGF-I and IGF-II to the IGF-1R.
Description & Specifications

Specifications

CD221 (Insulin-like Growth Factor-1 Receptor)
Murine
Flow Cytometry
Alexa Fluor 488
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
5μL (0.5μg)/test
1H7
IGF1R
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer