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CD21/CD35 Rat anti-Mouse, eFluor 450, Clone: eBio4E3 (4E3), eBioscience™

Rat Monoclonal Antibody

$187.05 - $404.55

Specifications

Antigen CD21/CD35
Clone eBio4E3 (4E3)
Host Species Rat
Gene Alias CR2/CR1, C3DR
Species Reactivity Mouse
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5016272 Life Technologies
LS48021280
25μg Each for $187.05
5016273 Life Technologies
LS48021282
100μg Each for $404.55
Specifications

Description

The monoclonal antibody eBio4E3 reacts with an eptiope shared by mouse CD21 (CR2) and CD35 (CR1). CD21 and CD35 are alternatively spliced transcripts from the Cr2 gene, which result in cell-surface proteins of 145 and 190 kDa, respectively. CD21 and CD35 are expressed by mature B cells, but not on thymocytes, peripheral T cells, erythrocytes or platelets. Furthermore, there is little evidence which demonstrates their expression on macrophages. CD21 is a receptor for complement component C3d and Epstein-Barr virus (EBV), and in association with CD19 and CD81, CD21 also participates in B-cell activation through the B cell receptor. Cr2 deficient mice display impaired inflammatory and humoral immune responses in vivo. The anti-mouse CD21/35 monoclonal antibody clones eBio4E3 and eBio8D9 do not cross-block each other suggesting that they bind to different epitopes.
Description & Specifications

Specifications

CD21/CD35
Rat
Mouse
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
eBio4E3 (4E3)
CR2/CR1, C3DR
Flow Cytometry
eFluor 450
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
0.2mg/mL