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CD21/CD35 Rat anti-Mouse, APC-eFluor 780, Clone: eBio8D9, eBioscience™

Rat Monoclonal Antibody

$172.55 - $448.05

Specifications

Antigen CD21/CD35
Clone eBio8D9
Host Species Rat
Gene Alias CR2/CR1, C3DR
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501124012

 
affymetrix
47021180
25μg Each for $172.55

501124013

 
affymetrix
47021182
100μg Each for $448.05
Description & Specifications

Specifications

Antigen CD21/CD35
Clone eBio8D9
Host Species Rat
Gene Alias CR2/CR1, C3DR
Species Reactivity Mouse
Applications Flow Cytometry
Regulatory Status RUO
Conjugate APC-eFluor 780
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.2mg/mL

The monoclonal antibody eBio8D9 reacts with an eptiope shared by mouse CD21 (CR2) and CD35 (CR1). CD21 and CD35 are alternatively spliced transcripts from the Cr2 gene, which produce cell-surface proteins of 145 and 190 kDa, respectively. CD21 and CD35 are expressed by mature B cells, but not on thymocytes, peripheral T cells, erythrocytes or platelets. Furthermore, there is some evidence which demonstrates their expression on macrophages. CD21 is a receptor for the complement component C3d and Epstein-Barr virus (EBV). In association with CD19 and CD81, CD21 also participates in B-cell activation through the B cell receptor. Cr2-deficient mice display impaired inflammatory and humoral immune responses in vivo.

The anti-mouse CD21/35 monoclonal antibody clones eBio4E3 and eBio8D9 do not cross-block each other, suggesting that they bind to different epitopes.