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CD209b (SIGN-R1) Armenian Hamster anti-Mouse, APC, Clone: 22D1, eBioscience™

Armenian Hamster Monoclonal Antibody

$158.05 - $404.55

Specifications

Antigen CD209b (SIGN-R1)
Clone 22D1
Host Species Armenian Hamster
Gene Alias C-type lectin
Species Reactivity Mouse
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501123106 Life Technologies
LS17209382
100μg Each for $404.55
501123105 Life Technologies
LS17209380
25μg Each for $158.05
Specifications

Description

The eBio22D1 monoclonal antibody reacts with mouse SIGNR1 (CD209b). SIGNR1 is a type II transmembrane C-type lectin that was identified in a search for mouse homologues of human DC-SIGN. It is expressed at high levels in splenic marginal zone macrophages and lymph node medullary macrophages, where it functions to uptake dextran polysaccharides, including the capsular polysaccharide of Streptococcus pneumoniae. It has also been demonstrated that SIGNR1 physically associates with TLR4/MD2, and it has been suggested that this association plays a role in recognition of LPS. Furthermore, recently it has been shown that SIGNR1 deficient mice have a defect in catabolism of the complement component C3, and that SIGNR1 binds directly to the complement C1 subcomponent, C1q to assemble a non-conventional C3 convertase. The eBio22D1 monoclonal antibody does not cross-react with the closely related SIGNR1, SIGNR2, SIGNR3 or SIGNR4.
Description & Specifications

Specifications

CD209b (SIGN-R1)
Armenian Hamster
Mouse
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
22D1
C-type lectin
Flow Cytometry
Allophycocyanin
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
0.2mg/mL