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CD201 (EPCR) Rat anti-Mouse, Biotin, Clone: eBio1560 (1560), eBioscience™

Rat Monoclonal Antibody

$158.05 - $404.55

Specifications

Antigen CD201 (EPCR)
Clone eBio1560 (1560)
Host Species Rat
Gene Alias Endothelial Protein C Receptor
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5011814

 
affymetrix
13-2012-80
25μg Each for $158.05

5011815

 
affymetrix
13-2012-82
100μg Each for $404.55
Description & Specifications

Specifications

Antigen CD201 (EPCR)
Clone eBio1560 (1560)
Host Species Rat
Gene Alias Endothelial Protein C Receptor
Species Reactivity Mouse
Applications Flow Cytometry
Applications Immunohistochemistry
Regulatory Status RUO
Conjugate Biotin
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The eBio1560 monoclonal antibody reacts with mouse Endothelial Protein C Receptor (EPCR, CD201), a 25kDa Type 1 transmembrane protein expressed on endothelial cells. EPCR exhibits sequence and structural homology with the MHC class I/CD1 family of proteins. EPCR is a ligand for Protein C and plays an important role in augmenting Protein C activation by the thrombin-thrombomodulin complex and in regulating blood coagulation and inflammation. Deletion of EPCR results in embryonic lethality, at least partically due to placental thrombosis.

Recently, it was demonstrated that EPCR expression identified cells in the bone marrow that are capable of hematopoietic reconstitution activity comparable to hematopoietic stem cells isolated with conventional methods. The eBio1560 monoclonal antibody can be used for the detection of these hematopoietic stem cells, however the eBiomRCR-16 monoclonal antibody should only be used for the detection of CD201 on endothelial cells.