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CD20 Rat anti-Mouse, Clone: AISB12, Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

$187.05 - $622.05

Specifications

Antigen CD20
Clone AISB12
Host Species Rat
Species Reactivity Mouse
Applications Flow Cytometry
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5014253

 
affymetrix
16020182
100μg Each for $187.05

5014254

 
affymetrix
16020185
500μg Each for $622.05
Description & Specifications

Specifications

Antigen CD20
Clone AISB12
Host Species Rat
Species Reactivity Mouse
Applications Flow Cytometry
Applications Functional Assay
Applications Western Blotting
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, no sodium azide
Concentration 1mg/mL

The AISB12 monoclonal antibody reacts with mouse CD20. CD20 is a B cell-specific 32kDa membrane protein involved in intracellular calcium regulation. CD20 expression begins after the induction of CD19 during development, and is coexpressed with IgM during the pre-B to immature B cell transition in bone marrow. Expression then increases during maturation with almost all mature cells expressing some level of CD20. The human CD20 antigen has proven to be an effective immunotherapeutic target in B cell lymphoma and several autoimmune diseases including rheumatoid arthritis and type I diabetes. CD20 consists of 4 transmembrane domains and a 44 amino acid extracellular loop domain where AISB12 binds.