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CD20 Mouse anti-Human, eFluor 660, Clone: L26, eBioscience™

Mouse Monoclonal Antibody

$159.72 - $308.88

Specifications

Antigen CD20
Clone L26
Host Species Murine
Gene Alias B1, MS4A2, Leu-16
Applications Immunohistochemistry (Formalin/Paraffin)
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501124259 Life Technologies
LS50020282
100μg Each for $308.88
501124258 Life Technologies
LS50020280
25μg Each for $159.72
Specifications

Description

The monoclonal antibody L26 recognizes human CD20, a two transmembrane spanning protein found on precursor and mature B lymphocytes. Expression is lost upon differentiation to plasma cells. The levels of CD20 are critical in evaluating malignant B lymphocytes including Non-Hodgkin’s Lymphoma, and Acute B cell, Chronic Lymphocytic and Hairy-Cell Leukemias. CD20 plays a role in B cell differentiation and activation. The structure of the protein shows a small extracellular loop with the carboxy and amino termini in the cytoplasmic compartment. The L26 antibody recognizes an epitope in the cytoplasmic domain and therefore requires permeabilization of the tissue for staining applications. Unlike many anti-CD20 antibodies that recognize the extracellular domain, the epitope recognized by L26 will not be blocked by therapeutic antibodies to CD20, like Rituximab.
Description & Specifications

Specifications

CD20
Murine
Immunohistochemistry (Formalin/Paraffin)
eFluor 660
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
0.2mg/mL
L26
B1, MS4A2, Leu-16
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer