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CD20 Mouse anti-Human, Clone: L26, eBioscience™

Mouse Monoclonal Antibody

$104.28 - $262.68

Specifications

Antigen CD20
Clone L26
Host Species Murine
Gene Alias B1, MS4A2, Leu-16
Applications Immunohistochemistry (Formalin/Paraffin),Immunohistochemistry (Frozen),Immunoprecipitation,Western Blot
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Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
50245548 Life Technologies
LS14020280
25μg Each for $104.28
50245549 Life Technologies
LS14020282
100μg Each for $262.68
Specifications

Description

The monoclonal antibody L26 recognizes human CD20, a two transmembrane spanning protein found on precursor and mature B lymphocytes. Expression is lost upon differentiation to plasma cells. The levels of CD20 are critical in evaluating malignant B lymphocytes including Non-Hodgkin’s Lymphoma, and Acute B cell, Chronic Lymphocytic and Hairy-Cell Leukemias. CD20 plays a role in B cell differentiation and activation. The structure of the protein shows a small extracellular loop with the carboxy and amino termini in the cytoplasmic compartment. The L26 antibody recognizes an epitope in the cytoplasmic domain and therefore requires permeabilization of the tissue for staining applications. Unlike many anti-CD20 antibodies that recognize the extracellular domain, the epitope recognized by L26 will not be blocked by therapeutic antibodies to CD20, like Rituximab.
Description & Specifications

Specifications

CD20
Murine
Immunohistochemistry (Formalin/Paraffin),Immunohistochemistry (Frozen),Immunoprecipitation,Western Blot
Unlabeled
Store at 2-8°C.
Monoclonal
0.5mg/mL
L26
B1, MS4A2, Leu-16
RUO
Purified
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer