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CD1d Mouse anti-Human, PerCP-eFluor 710, Clone: 51.1, eBioscience™

Mouse Monoclonal Antibody

$172.55 - $433.55

Specifications

Antigen CD1d
Clone 51.1
Host Species Mouse
Gene Alias R3, R3G1
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

50245847

 
affymetrix
46001641
25 tests Each for $172.55

50245848

 
affymetrix
46001642
100 tests Each for $433.55
Description & Specifications

Specifications

Antigen CD1d
Clone 51.1
Host Species Mouse
Gene Alias R3, R3G1
Species Reactivity Human
Applications Flow Cytometry
Regulatory Status RUO
Conjugate PerCP-eFluor 710
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.125μg)/test

The monoclonal antibody 51.1 reacts with human CD1d, a member of the CD1 family with similarity to the non-polymorphic MHC Class I-like molecules. CD1d is a highly conserved single transmembrane receptor of the Immunoglobulin Superfamily. CD1d can associate with beta-microglobulin another feature showing similarity to MHC class I molecules, but can also exist as a nonglycosylated protein not in association with beta microglobulin. This suggests different control mechanisms for presenting glycolipid containing molecules to CD1d reactive NKT cells. Expression of CD1d is found on B cells of the periphery, in resting monocytes and cortical thymocytes. On intestinal epithelial cells (IEC) expression is polarized. Expression can also be found at low levels intracellularly in hepatocytes. In HCV (hepatitis C virus) livers, CD1d is highly expressed compared to normal controls.

The 51.1 monoclonal antibody has been shown to have functional activity; blocking the interaction of CD1d transfected cells with NKT cells.