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CD1c Mouse anti-Human, APC, Clone: L161, eBioscience™

Mouse Monoclonal Antibody

$172.55 - $332.05

Specifications

Antigen CD1c
Clone L161
Host Species Mouse
Gene Alias BDCA-1
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5014830

 
affymetrix
17-0015-41
25 tests Each for $172.55

5014831

 
affymetrix
17001542
100 tests Each for $332.05
Description & Specifications

Specifications

Antigen CD1c
Clone L161
Host Species Mouse
Gene Alias BDCA-1
Species Reactivity Human
Applications Flow Cytometry
Regulatory Status RUO
Conjugate APC
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.06μg)/test

This L161 monoclonal antibody detects CD1c (also known as BDCA-1), a glycoprotein that is noncovalently linked to beta-2 microglobulin on thymocytes and antigen presenting cells such as dendritic and Langerhans cells. This molecule is also expressed on some circulating and marginal zone B cells, as well as in lymph nodes and germinal centers. CD1c is involved in the presentation of lipid antigens such as microbial fatty acids to effector T cells during the adaptive immune response. Finally, alternative splicing gives rise to three different isoforms of CD1c (soluble, membrane, and cytoplasmic/soluble isoforms).