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The HM-CCR5(7A4) monoclonal antibody binds the N terminal extracellular domain of mouse CCR5 with no crossreactivity to human CCR5.Description & Specifications
DescriptionCCR5 is the major co-receptor for macrophage-tropic isolates of HIV-1. CCR5, also known as CD195, is a seven transmembrane chemokine receptor capable of binding RANTES, MIP-1 alpha and MIP-1 beta. Knockout mice show a decreased recruitment of macrophages and increased susceptibility to infection. Protein and mRNA has been found in macrophages from thioglycolate-treated and activated T cells.
The HM-CCR5(7A4) monoclonal antibody binds the N terminal extracellular domain of mouse CCR5 with no crossreactivity to human CCR5.
|Store at 2-8°C. Do not freeze. Light-sensitive material.|
|MIP-1 alpha Receptor C-C chemokine receptor type 5, Cmkbr5|
|aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer|