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CD194 (CCR4) Mouse anti-Human, PE, Clone: D8SEE, eBioscience™

Mouse Monoclonal Antibody

$170.28 - $368.28

Specifications

Antigen CD194 (CCR4)
Clone D8SEE
Host Species Murine
Gene Alias C-C Motif Chemokine Receptor 4
Applications Flow Cytometry
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501122289 Life Technologies
LS12194941
25 Tests Each for $170.28
501122290 Life Technologies
LS12194942
100 Tests Each for $368.28
Specifications

Description

This D8SEE monoclonal antibody reacts with human CD194 (CCR4). CD194, also known as C-C Chemokine Receptor 4 (CCR4) is a member of the G protein-coupled receptor family, a large family characterized by seven transmembrane alpha helical domains. The ligands for CCR4 are CCL17 (TARC) and CCL22 (MDC), which direct the migration of target cells. CCR4 and its ligands, along with the other receptors CCR10 and CLA, are particularly important for the recruitment of T cells into the skin, where they may also play a role in adhesion and extravasation. Although CCR4 expression was originally believed to be restricted to Th2 cells, it has since been observed in some subsets of Th17, Treg, and Th1 cells. It is not expressed by naïve T cells, indicating a role in memory or effector function. Other cells that express CCR4 are activated NK cells, platelets, monocytes, and basophils.
Description & Specifications

Specifications

CD194 (CCR4)
Murine
Flow Cytometry
PE
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
5μL (0.25μg)/test
D8SEE
C-C Motif Chemokine Receptor 4
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer