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CD194 (CCR4) Mouse anti-Human, PE, Clone: D8SEE, eBioscience™

Mouse Monoclonal Antibody

$187.05 - $404.55

Specifications

Antigen CD194 (CCR4)
Clone D8SEE
Host Species Mouse
Gene Alias C-C Motif Chemokine Receptor 4
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501122290

 
affymetrix
12194942
100 tests Each for $404.55

501122289

 
affymetrix
12194941
25 tests Each for $187.05
Description & Specifications

Specifications

Antigen CD194 (CCR4)
Clone D8SEE
Host Species Mouse
Gene Alias C-C Motif Chemokine Receptor 4
Species Reactivity Human
Applications Flow Cytometry
Regulatory Status RUO
Conjugate PE
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.25μg)/test

This D8SEE monoclonal antibody reacts with human CD194 (CCR4). CD194, also known as C-C Chemokine Receptor 4 (CCR4) is a member of the G protein-coupled receptor family, a large family characterized by seven transmembrane alpha helical domains. The ligands for CCR4 are CCL17 (TARC) and CCL22 (MDC), which direct the migration of target cells. CCR4 and its ligands, along with the other receptors CCR10 and CLA, are particularly important for the recruitment of T cells into the skin, where they may also play a role in adhesion and extravasation. Although CCR4 expression was originally believed to be restricted to Th2 cells, it has since been observed in some subsets of Th17, Treg, and Th1 cells. It is not expressed by naïve T cells, indicating a role in memory or effector function. Other cells that express CCR4 are activated NK cells, platelets, monocytes, and basophils.