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CD194 (CCR4) Mouse anti-Human, APC, Clone: D8SEE, eBioscience™

Mouse Monoclonal Antibody

$201.55 - $419.05

Specifications

Antigen CD194 (CCR4)
Clone D8SEE
Host Species Murine
Gene Alias C-C Motif Chemokine Receptor 4
Species Reactivity Human
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501123095 Life Technologies
LS17194941
25 Tests Each for $201.55
501123096 Life Technologies
LS17194942
100 Tests Each for $419.05
Specifications

Description

This D8SEE monoclonal antibody reacts with human CD194 (CCR4). CD194, also known as C-C Chemokine Receptor 4 (CCR4) is a member of the G protein-coupled receptor family, a large family characterized by seven transmembrane alpha helical domains. The ligands for CCR4 are CCL17 (TARC) and CCL22 (MDC), which direct the migration of target cells. CCR4 and its ligands, along with the other receptors CCR10 and CLA, are particularly important for the recruitment of T cells into the skin, where they may also play a role in adhesion and extravasation. Although CCR4 expression was originally believed to be restricted to Th2 cells, it has since been observed in some subsets of Th17, Treg, and Th1 cells. It is not expressed by naïve T cells, indicating a role in memory or effector function. Other cells that express CCR4 are activated NK cells, platelets, monocytes, and basophils.
Description & Specifications

Specifications

CD194 (CCR4)
Murine
Human
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
D8SEE
C-C Motif Chemokine Receptor 4
Flow Cytometry
Allophycocyanin
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
5μL (0.125μg)/test