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CD193 (CCR3) Mouse anti-Human, APC, Clone: 5E8-G9-B4, eBioscience™

Mouse Monoclonal Antibody

$201.55 - $433.55

Specifications

Antigen CD193 (CCR3)
Clone eBio5E8-G9-B4 (5E8-G9-B4)
Host Species Mouse
Gene Alias CKR3
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5015113

 
affymetrix
17-1939-41
25 tests Each for $201.55

5015114

 
affymetrix
17-1939-42
100 tests Each for $433.55
Description & Specifications

Specifications

Antigen CD193 (CCR3)
Clone eBio5E8-G9-B4 (5E8-G9-B4)
Host Species Mouse
Gene Alias CKR3
Species Reactivity Human
Applications Flow Cytometry
Regulatory Status RUO
Conjugate APC
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.25μg)/test

The eBio5E8-G9-B4 monoclonal antibody reacts with human CD193 (CCR3, CKR3). CD193 is a member of the seven transmembrane G-protein coupled receptor (GPCR) family, and is a high affinity chemokine receptor for the chemokines eotaxin-1 (CCL11), eotaxin-2 (CCL24), eotaxin-3 (CCL26) and MCP-4 (CCL13), but has also been reported to bind RANTES, MCP-3 and MCP-4. CD193 is highly expressed on the surface of eosinophils, and is the key eosinophil chemokine receptor responsible for the regulation of eosinophil migration and function. In addition to eosinophils, CD193 is also expressed on CD4+ TH2 cells, basophils, mast cells, mononuclear phagocytes, platelets, CD34+ hematopoietic progenitors and airway epithelial cells. CD193 likely plays an important role in the migration of eosinophils in allergic airway inflammation and asthma. CD193 can also serve as a receptor for HIV-1 cell entry.