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CD193 (CCR3) Mouse anti-Human, APC, Clone: 5E8-G9-B4, eBioscience™

Mouse Monoclonal Antibody

$183.48 - $394.68

Specifications

Antigen CD193 (CCR3)
Clone eBio5E8-G9-B4 (5E8-G9-B4)
Host Species Murine
Gene Alias CKR3
Applications Flow Cytometry
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5015113 Life Technologies
LS17193941
25 Tests Each for $183.48
5015114 Life Technologies
LS17193942
100 Tests Each for $394.68
Specifications

Description

The eBio5E8-G9-B4 monoclonal antibody reacts with human CD193 (CCR3, CKR3). CD193 is a member of the seven transmembrane G-protein coupled receptor (GPCR) family, and is a high affinity chemokine receptor for the chemokines eotaxin-1 (CCL11), eotaxin-2 (CCL24), eotaxin-3 (CCL26) and MCP-4 (CCL13), but has also been reported to bind RANTES, MCP-3 and MCP-4. CD193 is highly expressed on the surface of eosinophils, and is the key eosinophil chemokine receptor responsible for the regulation of eosinophil migration and function. In addition to eosinophils, CD193 is also expressed on CD4+ TH2 cells, basophils, mast cells, mononuclear phagocytes, platelets, CD34+ hematopoietic progenitors and airway epithelial cells. CD193 likely plays an important role in the migration of eosinophils in allergic airway inflammation and asthma. CD193 can also serve as a receptor for HIV-1 cell entry.
Description & Specifications

Specifications

CD193 (CCR3)
Murine
Flow Cytometry
Allophycocyanin
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
5μL (0.25μg)/test
eBio5E8-G9-B4 (5E8-G9-B4)
CKR3
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer