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CD183 (CXCR3) Armenian Hamster anti-Mouse, PE, Clone: CXCR3-173, eBioscience™

Armenian Hamster Monoclonal Antibody

$147.84 - $394.68

Specifications

Antigen CD183 (CXCR3)
Clone CXCR3-173
Host Species Armenian Hamster
Gene Alias C-X-C chemokine receptor type 3, IP-10 receptor
Species Reactivity Mouse
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501122284 Life Technologies
LS12183180
25μg Each for $147.84
501122285 Life Technologies
LS12183182
100μg Each for $394.68
Specifications

Description

The monoclonal antibody CXCR3-173 recognizes mouse CD183 also known as CXCR3. CD183 is a seven transmembrane G-protein liked chemokine receptor which binds three ligands; CXCL9 (mig), CXCL10 (IP-10)and CXCL11 (ITAC). CD183 as been shown to play a role in CD4 T cell responses to grafts. CXCR3 knockout mice have compromised allograft rejection responses. Expression is found on NK cells, a subset of T lymphocytes and a subset of Tregs as well as preferential expression on Th1-polarized cells.

The antibody CXCR3-173 has been shown to affect chemotaxis in response to ligand. The presence of ligand eliminates staining with the antibody. In vivo addition of the antibody delays cardiac and pancreatic islet allograft rejection.
Description & Specifications

Specifications

CD183 (CXCR3)
Armenian Hamster
Mouse
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
CXCR3-173
C-X-C chemokine receptor type 3, IP-10 receptor
Flow Cytometry
PE
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
0.2mg/mL