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CD183 (CXCR3) Armenian Hamster anti-Mouse, Clone: CXCR3-173, Functional Grade, eBioscience™

Armenian Hamster Monoclonal Antibody, Functional Grade

$223.08 - $434.28

Specifications

Antigen CD183 (CXCR3)
Clone CXCR3-173
Host Species Armenian Hamster
Gene Alias C-X-C chemokine receptor type 3, IP-10 receptor
Applications Flow Cytometry,Functional Assay
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5014494 Life Technologies
LS16183185
500μg Each for $434.28
5014493 Life Technologies
LS16183181
50μg Each for $223.08
Specifications

Description

The monoclonal antibody CXCR3-173 recognizes mouse CD183 also known as CXCR3. CD183 is a seven transmembrane G-protein liked chemokine receptor which binds three ligands; CXCL9 (mig), CXCL10 (IP-10)and CXCL11 (ITAC). CD183 as been shown to play a role in CD4 T cell responses to grafts. CXCR3 knockout mice have compromised allograft rejection responses. Expression is found on NK cells, a subset of T lymphocytes and a subset of Tregs as well as preferential expression on Th1-polarized cells.

The antibody CXCR3-173 has been shown to affect chemotaxis in response to ligand. The presence of ligand eliminates staining with the antibody. In vivo addition of the antibody delays cardiac and pancreatic islet allograft rejection.
Description & Specifications

Specifications

CD183 (CXCR3)
Armenian Hamster
Flow Cytometry,Functional Assay
Unlabeled
Store at 2-8°C.
Monoclonal
1mg/mL
CXCR3-173
C-X-C chemokine receptor type 3, IP-10 receptor
RUO
Purified
Primary
aqueous buffer, no sodium azide