missing translation for 'onlineSavingsMsg'
Learn More
Please login to your online account to display your discounted pricing

CD182 (CXCR2) Mouse anti-Human, Clone: eBio5E8-C7-F10 (5E8-C7-F10), eBioscience™

Mouse Monoclonal Antibody

$77.88 - $341.88

Specifications

Antigen CD182 (CXCR2)
Clone eBio5E8-C7-F10 (5E8-C7-F10)
Host Species Murine
Gene Alias Interleukin-8 Receptor B, IL8RB, IL98Rb
Applications Flow Cytometry
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5012950 Life Technologies
LS14182980
25μg Each for $77.88
5012951 Life Technologies
LS14182982
100μg Each for $143.88
5012952 Life Technologies
LS14182985
500μg Each for $341.88
Specifications

Description

The eBio5E8-C7-F10 monoclonal antibody reacts with human CD182 (CXCR2, IL-8Rβ). CD182 is a 67-70kDa member of the seven-transmembrane spanning G-protein coupled receptor (GPCR) family. CD182 is expressed as a homodimer, or a heterodimer with CD181 (CXCR1, IL-8Rα) and is expressed on granulocytes, NK cells, a subset of T cells, mast cells, monocytes, endothelial cells, megakaryocytes and oligodendrocytes. Binding of it's ligands, which include IL-8, NAP-2, GCP-2 and GRO-α, -β and -γ, induces several biological outcomes such as cell activation, chemotaxis, proliferation and angiogenesis. There are several functional differences between CD181 and CD182. Both receptors are able to mediate chemotaxis and intracellular calcium changes, but only CD181 mediates phospolipase D activation and respiratory burst. Furthermore, studies have shown that IL-8 predominantly mediates its effects on neutrophil function through CD181.
Description & Specifications

Specifications

CD182 (CXCR2)
Murine
Flow Cytometry
Unlabeled
Store at 2-8°C.
Monoclonal
0.5mg/mL
eBio5E8-C7-F10 (5E8-C7-F10)
Interleukin-8 Receptor B, IL8RB, IL98Rb
RUO
Purified
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer