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CD178 (CD95 Ligand) Mouse anti-Human, Clone: NOK-1, Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

$158.05 - $477.05

Specifications

Antigen CD178 (CD95 Ligand)
Clone NOK-1
Host Species Mouse
Gene Alias CD95L, Fas ligand, FasL
Species Reactivity Human
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 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501123013

 
affymetrix
16991985
500μg Each for $477.05

5014794

 
affymetrix
16-9919-81
50μg Each for $158.05
Description & Specifications

Specifications

Antigen CD178 (CD95 Ligand)
Clone NOK-1
Host Species Mouse
Gene Alias CD95L, Fas ligand, FasL
Species Reactivity Human
Applications Flow Cytometry
Applications Functional Assay
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, no sodium azide
Concentration 1mg/mL

The NOK-1 monoclonal antibody reacts with human Fas (CD95) Ligand, a 40kDa type II transmembrane glycoprotein. FasL is a member of the TNF family and is expressed by neutrophils, monocytes, and activated T cells and NK cells. The interaction of FasL with its receptor (CD95, Fas) induces Fas-mediated killing of lymphocytes. Human FasL is cleaved from the surface by matrix metalloproteinases (MMPs), resulting in a 26kDa soluble form. Therefore for optimal detection of surface FasL on activated peripheral blood cells, incubation of cells with an MMP inhibitor is recommended.