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CD172a (SIRP alpha) Mouse anti-Rat, APC, Clone: OX41, eBioscience™

Mouse Monoclonal Antibody

$157.08 - $341.88

Specifications

Antigen CD172a (SIRP alpha)
Clone OX41
Host Species Murine
Gene Alias SIRPa, SHPS1
Applications Flow Cytometry
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501123093 Life Technologies
LS17172082
100μg Each for $341.88
501123092 Life Technologies
LS17172080
25μg Each for $157.08
Specifications

Description

The monoclonal antibody OX41 reacts with rat CD172a, which is also known as signal-regulatory protein alpha (SIRPa). SIRP family members are transmembrane glycoproteins with 3 Ig-like extracellular domains and a cytoplasmic tail containing 2 immunocreceptor tyrosine-based inhibition motifs. CD172a is expressed by monocytes, macrophages, granulocytes, dendritic cells, and neurons. SIRPa association with CD47 inhibits phagocytosis of CD47 presenting cells. Studies suggest that SIRPa ligation prevents phagocytosis by inactivating paxillin and cofilin, proteins involved in cytoskeleton remodeling.
Description & Specifications

Specifications

CD172a (SIRP alpha)
Murine
Flow Cytometry
Allophycocyanin
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
0.2mg/mL
OX41
SIRPa, SHPS1
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer