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CD170 (Siglec F) Rat anti-Mouse, Clone: 1RNM44N, eBioscience™

Rat Monoclonal Antibody

$146.52 - $348.48

Specifications

Antigen CD170 (Siglec F)
Clone 1RNM44N
Host Species Rat
Species Reactivity Mouse
Applications Flow Cytometry,Immunohistochemistry (Frozen)
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501122660 Life Technologies
LS14170280
25μg Each for $146.52
501122661 Life Technologies
LS14170282
100μg Each for $348.48
Specifications

Description

This 1RNM44N monoclonal antibody recognizes mouse CD170, also known as Siglec F. Siglec F is a cell surface lectin belonging to the Ig superfamily that binds glycoconjugates containing sialic acids that are commonly found on various cell types. The cytoplasmic domain of Siglec F contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) that initiates intracellular signaling upon ligand binding. Siglec F is expressed mostly on eosinophils and alveolar macrophages and lower levels of this receptor have also been reported on immature myelomonocytic cells. Mouse Siglec F is a functional ortholog of human Siglec 8, however, unlike human Siglec 8, mouse Siglec F is not expressed on mast cells.

This 1RNM44N antibody will recognize a formaldehyde-fixed epitope.
Description & Specifications

Specifications

CD170 (Siglec F)
Rat
Flow Cytometry,Immunohistochemistry (Frozen)
Unlabeled
Store at 2-8°C.
Monoclonal
0.5mg/mL
1RNM44N
Mouse
RUO
Purified
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer