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CD169 (Siglec-1) Mouse anti-Human, PE, Clone: 7-239, eBioscience™

Mouse Monoclonal Antibody

$172.55 - $433.55

Specifications

Antigen CD169 (Siglec-1)
Clone 7-239
Host Species Mouse
Gene Alias Sialoadhesin
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5010681

 
life technologies
LS12169941
25 tests Each for $172.55

5010682

 
life technologies
LS12169942
100 tests Each for $433.55
Description & Specifications

Specifications

Antigen CD169 (Siglec-1)
Clone 7-239
Host Species Mouse
Gene Alias Sialoadhesin
Species Reactivity Human
Applications Flow Cytometry
Regulatory Status RUO
Conjugate PE
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.5μg)/test

This 7-239 monoclonal antibody reacts with human CD169, also known as Siglec-1 and Sialoadhesin. This type I transmembrane protein is a member of the sialic acid binding Ig-like lectin (Siglec) family. Expressed on macrophages and dendritic cells in peripheral blood, lymph nodes, and spleen in humans, CD169 binds glycoproteins and glycolipids containing N-acetylneuraminyl alpha 2-3-galactose. CD169 expression can also be induced on CD14+ monocytes by interferon-alpha and interferon-gamma to mediate HIV-1 infection. Finally, CD169 has also been shown to be involved in antigen presentation to invariant NK T cells.

This monoclonal antibody has been reported to inhibit erythrocyte binding to CD169-expressing cells.