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CD166 (ALCAM) Mouse anti-Human, PE, Clone: 3A6, eBioscience™

Mouse Monoclonal Antibody

$143.88 - $355.08

Specifications

Antigen CD166 (ALCAM)
Clone 3A6
Host Species Murine
Gene Alias Activated leukocyte cell adhesion molecule
Applications Flow Cytometry
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501122280 Life Technologies
LS12166841
25 Tests Each for $143.88
501122281 Life Technologies
LS12166842
100 Tests Each for $355.08
Specifications

Description

This 3A6 monoclonal antibody reacts with human CD166, which is also known as activated leukocyte cell adhesion molecule (ALCAM). CD166 is an immunoglobulin superfamily cell adhesion molecule that is broadly expressed on developing and adult hematopoietic (e.g., activated T and B cells, monocytes, and dendritic cells) and non-hematopoietic (e.g., neural, endothelial, and epithelial) tissues. CD166 has also been detected in melanoma, colorectal carcinoma, as well as cancers of the breast, prostate, and bladder. CD166 mediates cell-cell adhesion by forming low-affinity homophilic interactions (ALCAM-ALCAM) or high-affinity heterophilic interactions with its ligand CD6 (ALCAM-CD6). CD166 plays a role in development, inflammation, and neutrophil migration. Moreover, its expression can be used as a prognostic marker for several cancers and has been reported to be a cancer stem cell marker.

The 3A6 antibody has been reported to induce the internalization of CD166 and its recycling back to the cell surface.
Description & Specifications

Specifications

CD166 (ALCAM)
Murine
Flow Cytometry
PE
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
5μL (0.06μg)/test
3A6
Activated leukocyte cell adhesion molecule
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer