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CD163 Mouse anti-Human, Biotin, Clone: eBioGHI/61 (GHI/61), eBioscience™

Mouse Monoclonal Antibody

$129.05 - $262.68

Specifications

Antigen CD163
Clone eBioGHI/61 (GHI/61)
Host Species Murine
Gene Alias M130, Haemoglobin Scavenger Receptor, Macrophage marker
Species Reactivity Human
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5011788 Life Technologies
LS13163980
25μg Each for $129.05
5011789 Life Technologies
LS13163982
100μg Each for $262.68
Specifications

Description

The eBioGHI/61 monoclonal antibody reacts with human CD163 (Haemoglobin Scavenger Receptor, M130), a member of the macrophage scavenger receptor family. CD163 is expressed by tissue macrophages, circulating blood monocytes, and some reports suggest that it may also be expressed by haematopoietic progenitor cells. CD163 functions as a high affinity scavenger receptor for the complex of haemoglobin and haptoglobin which forms to clear haemoglobin from the blood. The high affinity for CD163 is specific for the haemoglobin-haptoglobin complex, whereas haemoglobin or haptoglobin display no to low affinity toward CD163. Upon ligand binding, CD163 initiates signal transduction which leads to the production of IL-6 and IL-10. Furthermore, it has been demonstrated that cytokines such as IL-6 and IL-10 can induce expression of CD163, whereas proinflammatory stimuli, such as LPS or TNF alpha, can cause shedding of a soluble form of CD163, whose function is unclear.
Description & Specifications

Specifications

CD163
Murine
Human
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
eBioGHI/61 (GHI/61)
M130, Haemoglobin Scavenger Receptor, Macrophage marker
Flow Cytometry
Biotin
Store at 2-8°C. Do not freeze.
Monoclonal
0.5mg/mL