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CD161 Mouse anti-Human, APC, Clone: HP-3G10, eBioscience™

Mouse Monoclonal Antibody

$201.55 - $419.05

Specifications

Antigen CD161
Clone HP-3G10
Host Species Mouse
Gene Alias NKR-P1A, NKRP1A
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5015105

 
affymetrix
17-1619-41
25 tests Each for $201.55

5015106

 
affymetrix
17-1619-42
100 tests Each for $419.05
Description & Specifications

Specifications

Antigen CD161
Clone HP-3G10
Host Species Mouse
Gene Alias NKR-P1A, NKRP1A
Species Reactivity Human
Applications Flow Cytometry
Regulatory Status RUO
Conjugate APC
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.25μg)/test

This HP-3G10 monoclonal antibody reacts with CD161 (also known as NKR-P1A), a member of the C-type lectin superfamily. The human homologue of NK1.1 in C57BL/6 mice, CD161 is expressed on natural killer cells and is upregulated in response to IL-12. CD161 can also be detected on various T cell subsets, including memory/effector CD4+ T cells, CD8+ T cells, gamma delta TCR T cells, and a subset of CD3+ thymocytes. Finally, CD161 expression has been demonstrated on human Th17 CD4+ T cells. The function of this receptor is unclear although studies suggest a possible stimulatory role. Nevertheless, Lectin-like transcript-1 (LLT1), which is also known as osteoclast inhibitory lectin, has been identified as the ligand for CD161.