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CD160 Rat anti-Mouse, Clone: eBioCNX46-3 (CNX46-3), Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

$143.88 - $368.28

Specifications

Antigen CD160
Clone eBioCNX46-3 (CNX46-3)
Host Species Rat
Gene Alias BY55
Applications Flow Cytometry,Functional Assay,Immunoprecipitation,Western Blot
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5014486 Life Technologies
LS16160181
50μg Each for $143.88
5014488 Life Technologies
LS16160185
500μg Each for $368.28
Specifications

Description

CD160 is a glycosylphosphatidylinositol (GPI)-anchored Ig-like glycoprotein first identified on human lymphocytes with the monoclonal antibody BY55. In mice, CD160 is expressed on almost all (intestinal intraepithelial lymphocytes) iIELs, NKT cells, most TCRγδ T cells, few NK cells and a minor subset of CD8+ T cells. Murine CD160 has been shown to bind to a wide range of classical and non classical MHC class I molecules and regulate NK cell activation. In vitro, CD3 activation of murine CD8+ T cells increases the expression of CD160 and induces the release of soluble CD160 (sCD160). In human, CD160 mAb cross-linking triggers TNF alpha, IFN gamma and IL-6 cytokine production by peripheral blood NK cells and inhibits tube formation and induces apoptosis of endothelial cells. In mice, cross-linking of CD160 with the CNX46-3 antibody regulates NK cell activation both positively and negatively, depending on the stimulus.
Description & Specifications

Specifications

CD160
Rat
Flow Cytometry,Functional Assay,Immunoprecipitation,Western Blot
Unlabeled
Store at 2-8°C.
Monoclonal
1mg/mL
eBioCNX46-3 (CNX46-3)
BY55
RUO
Purified
Primary
aqueous buffer, no sodium azide