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This monoclonal antibody has been shown to block Fc receptor functions.Description & Specifications
DescriptionThis B73.1 monoclonal antibody reacts with human CD16, a member of the Fc receptor family also known as Fc gamma RIIIa and Fc gamma RIIIb. This 50-65kDa receptor is expressed on natural killer cells, neutrophils, monocytes, and macrophages. Crosslinking of CD16 in natural killer cells and monocytes results in activation of the MAPK and PI3K signaling pathways, thus regulating the production of TNF alpha, IL-6, and IL-1 beta.
This monoclonal antibody has been shown to block Fc receptor functions.
|aqueous buffer, no sodium azide|
|Low Affinity IgG Receptor 3, FCGR3a, FCGR3, IGFR3|
|Flow Cytometry,Functional Assay|
|Store at 2-8°C.|