missing translation for 'onlineSavingsMsg'
Learn More
Please login to your online account to display your discounted pricing

CD16 Mouse anti-Human, Biotin, Clone: eBioCB16 (CB16), eBioscience™

Mouse Monoclonal Antibody

$117.48 - $223.08

Specifications

Antigen CD16
Clone eBioCB16 (CB16)
Host Species Murine
Gene Alias Low Affinity IgG Receptor 3, FCGR3a, FCGR3, IGFR6
Species Reactivity Human
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5011451 Life Technologies
LS13016880
25μg Each for $117.48
5011452 Life Technologies
LS13016882
100μg Each for $223.08
Specifications

Description

The eBioCB16 monoclonal antibody recognizes CD16 (Fc gammaRIII), the low-affinity receptor for IgG with an apparent molecular weight of 50-80 kDa. CD16 is represented by two similar genes, CD16A (Fc gammaRIIIA), which exists as a hetero-oligomeric polypeptide-anchored form in macrophages and NK cells and CD16B (Fc gammaRIIIB), which exist as a monomeric GPI-anchored form in neutrophils. Furthermore, there are two known polymorphisms of CD16B, NA-1 and NA-2. Individuals homozygous for NA-2 show a lower phagocytic capacity compared with NA-1. CD16 binds IgG in the form of immune complexes and shows preferential binding of IgG1 and IgG3 isotypes and minimal binding of IgG2 and IgG4. Upon IgG binding, both CD16 isoforms initiate signal transduction cascades that lead to a variety of responses including antibody-dependent cell-mediated cytotoxicity (ADCC), phagocytosis, degranulation and proliferation.
Description & Specifications

Specifications

CD16
Murine
Human
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
eBioCB16 (CB16)
Low Affinity IgG Receptor 3, FCGR3a, FCGR3, IGFR6
Flow Cytometry
Biotin
Store at 2-8°C. Do not freeze.
Monoclonal
0.5mg/mL