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CD158f Mouse anti-Human, PE, Clone: UP-R1, eBioscience™

Mouse Monoclonal Antibody

$201.55 - $462.55

Specifications

Antigen CD158f
Clone UP-R1
Host Species Mouse
Gene Alias KIR2DL5/S5, KIR
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5010669

 
affymetrix
12-1588-41
25 tests Each for $201.55

5010670

 
affymetrix
12-1588-42
100 tests Each for $462.55
Description & Specifications

Specifications

Antigen CD158f
Clone UP-R1
Host Species Mouse
Gene Alias KIR2DL5/S5, KIR
Species Reactivity Human
Applications Flow Cytometry
Regulatory Status RUO
Conjugate PE
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.25μg)/test

This UP-R1 monoclonal antibody recognizes human CD158f, also known as KIR2DL5. CD158f is an inhibitory receptor and a member of the KIR (Killer cell Ig-like receptors) family of receptors, which recognizes subsets of HLA alleles. Expression is found mainly on a subset of NK cells with minimal expression also present on a minor subset of T lymphocytes in some individuals. This new member of the family is highly polymorphic and expression is not found on many human donors. Activation of the receptor and tyrosine phosphoryaltion recruits SHP-2 and SHP-1 to the ITIM cytoplasmic domain.

The UP-R1 antibody has been shown to inhibit NK cytotoxicity.