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CD158f Mouse anti-Human, APC, Clone: UP-R1, eBioscience™

Mouse Monoclonal Antibody

$230.55 - $462.55

Specifications

Antigen CD158f
Clone UP-R1
Host Species Murine
Gene Alias KIR2DL5/S5, KIR
Species Reactivity Human
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5015101 Life Technologies
LS17158841
25 Tests Each for $230.55
5015102 Life Technologies
LS17158842
100 Tests Each for $462.55
Specifications

Description

This UP-R1 monoclonal antibody recognizes human CD158f, also known as KIR2DL5. CD158f is an inhibitory receptor and a member of the KIR (Killer cell Ig-like receptors) family of receptors, which recognizes subsets of HLA alleles. Expression is found mainly on a subset of NK cells with minimal expression also present on a minor subset of T lymphocytes in some individuals. This new member of the family is highly polymorphic and expression is not found on many human donors. Activation of the receptor and tyrosine phosphoryaltion recruits SHP-2 and SHP-1 to the ITIM cytoplasmic domain.

The UP-R1 antibody has been shown to inhibit NK cytotoxicity.
Description & Specifications

Specifications

CD158f
Murine
Human
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
UP-R1
KIR2DL5/S5, KIR
Flow Cytometry
Allophycocyanin
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
5μL (0.25μg)/test