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CD157 Mouse anti-Human, PE-Cy7, Clone: eBioSY11B5 (SY11B5), eBioscience™

Mouse Monoclonal Antibody

$172.55 - $404.55

Specifications

Antigen CD157
Clone eBioSY11B5 (SY11B5)
Host Species Mouse
Gene Alias BST-1, BP-3/IF-7
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501123343

 
affymetrix
25157941
25 tests Each for $172.55

501123344

 
affymetrix
25157942
100 tests Each for $404.55
Description & Specifications

Specifications

Antigen CD157
Clone eBioSY11B5 (SY11B5)
Host Species Mouse
Gene Alias BST-1, BP-3/IF-7
Species Reactivity Human
Applications Flow Cytometry
Regulatory Status RUO
Conjugate PE-Cy7
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.125μg)/test

The eBioSY11B5 monoclonal antibody recognizes human CD157 (Mo5, BST-1). CD157 is a 42-45 kDa, GPI-anchored protein with structural and functional similarities with CD38. CD157 was initially cloned because of its expression on monocytes and macrophages, and was subsequently discovered to be the same protein named BST-1, discovered for its expression on bone marrow stromal cells and its ability to stimulate the proliferation of a mouse pre-B cell line. CD157 is a pleiotropic ectoenzyme and is thought to act independently as an enzyme and receptor. Similar to CD38, CD157 is involved in the metabolism of NAD+ and this activity may be involved in regulating intracellular Ca2+ levels. As a receptor, upon binding of its putative ligand, CD157 is thought to initiate a signal transduction cascade resulting in the phosphorylation of cytoplasmic proteins including focal adhesion kinase (FAK). The mechanism and functional significance of CD157-initiated signal transduction remain to be fully characterized.