CD155/PVR (Poliovirus Receptor) Ab-1 Mouse Monoclonal Antibody, Epredia™

Description

PVR is a member of Ig-superfamily with 3 Ig-domains in arrangement V-C-C. Four mRNAs are produced from a single gene for PVR, (mapped to human chromosome band 19q13.1-13.2). Two of the mRNAs (called H20A and H20B or α and κ,) encode cell surface molecules of about 43kDa and 45kDa polypeptide backbones, respectively. Two other splice variants, Β and γ, encode secreted molecules of about 44kDa. The cytoplasmic tails are short (aa 35-50) and are rich in serine phosphorylated residues.

Host Species: Mouse

Clone: D171

Isotype: IgG1

Species Reactivity: Human and Monkey. Does not react with pig, dog, rabbit, rat, hamster and mouse. Others not known.

Epitope: aa 35-50

Immunogen: HeLa cells

Molecular Weight: 60-80kDa

Positive Control: HeLa, SV 80, HEp-2, RD, A431, HL-60, U-937 cells; Monkey Vero, GMK, or TC-7 cells

Cellular Localization: Membrane

Recommended for:

• Western Blotting (Not suitable)
• Immunofluorescence
• Flow Cytometry
• Inhibits Replication of Poliovirus in HeLa Cells

Note:

USA: RUO; Int'l: RUO