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CD154 (CD40 Ligand) Armenian Hamster anti-Mouse, Clone: MR1, Functional Grade, eBioscience™

Armenian Hamster Monoclonal Antibody, Functional Grade

$114.55 - $433.55

Specifications

Antigen CD154 (CD40 Ligand)
Clone MR1
Host Species Armenian Hamster
Gene Alias CD40L
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5014482

 
affymetrix
16154181
50μg Each for $114.55

5014483

 
affymetrix
16154182
100μg Each for $216.05

5014484

 
affymetrix
16154185
500μg Each for $433.55
Description & Specifications

Specifications

Antigen CD154 (CD40 Ligand)
Clone MR1
Host Species Armenian Hamster
Gene Alias CD40L
Species Reactivity Mouse
Applications Flow Cytometry
Applications Functional Assay
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, no sodium azide
Concentration 1mg/mL

The MR1 monoclonal antibody reacts with mouse CD154, a 39kDa transmembrane glycoprotein also known as CD40 ligand (CD40L). CD154 is expressed transiently by activated T cells. Through its binding to CD40 on antigen presenting cells (APC) including B cells, monocytes/macrophages, and dendritic cells, it serves a crucial function in T cell-APC cognate interaction. CD154-interaction with CD40 transduces signals for T-dependent B cell activation and induces B cells to enter the cell cycle.

For staining for flow cytometric analysis, it is important to stimulate enriched T cells or enriched CD4 cells (using depletion strategy) prior to staining with MR1.