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CD152 (CTLA-4) Golden Syrian Hamster anti-Mouse, Clone: 9H10, Functional Grade, eBioscience™

Golden Syrian Hamster Monoclonal Antibody, Functional Grade

$129.05 - $404.55

Specifications

Antigen CD152 (CTLA-4)
Clone 9H10
Host Species Golden Syrian Hamster
Gene Alias CTLA4
Species Reactivity Mouse
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5014475 Life Technologies
LS16152181
50μg Each for $129.05
5014476 Life Technologies
LS16152182
100μg Each for $230.55
5014477 Life Technologies
LS16152185
500μg Each for $404.55
Specifications

Description

The 9H10 monoclonal antibody reacts with mouse CD152, also known as the cytotoxic T lymphocyte antigen-4 (CTLA-4). CTLA-4, a protein with structural similarities to CD28, is expressed on activated T cells and binds the B7 family members, CD80 (B7-1) and CD86 (B7-2), with higher affinity than CD28 does. CTLA-4 and CD28 appear to deliver opposing signals to T cells: while CD28 is a potent costimulator, CTLA-4 restricts the progression of T cells to an activated state by inhibiting IL-2 secretion and cellular proliferation. The cytoplasmic portion of CTLA-4 contains ER retention motifs, resulting in a large proportion of newly synthesized CTLA-4 in response to TCR signaling to be localized intracellularly.
Description & Specifications

Specifications

CD152 (CTLA-4)
Golden Syrian Hamster
Mouse
RUO
Purified
Primary
aqueous buffer, no sodium azide
9H10
CTLA4
Flow Cytometry,Functional Assay
Unlabeled
Store at 2-8°C.
Monoclonal
1mg/mL