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Thermo Scientific™ Lab Vision™ CD15 Ab-3, Mouse Monoclonal Antibody


Ensure accurate, reproducible results in immunohistochemistry and flow cytometry procedures with Thermo Scientific™ CD15 Ab-3, Mouse Monoclonal Antibody.

Manufacturer: thermo scientific™ lab vision™  MS1259P1ABX

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Catalog No. MS1259P1ABX

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Description & Specifications

Specifications

Antigen CD15 Ab-3
Applications Flow Cytometry
Applications Immunohistochemistry (Paraffin)
Classification Monoclonal
Clone MMA; same as LeuM1
Concentration 1mg/mL
Conjugate Unlabeled
Cross Reactivity Human
Format Concentrated
Host Species Mouse
Immunogen U937 histiocytic cell line
Isotype IgM kappa
Quantity 100µL
Regulatory Status IVD
Research Discipline Oncogenesis
Type Primary

Ensure accurate, reproducible results in immunohistochemistry and flow cytometry procedures with Thermo Scientific™ CD15 Ab-3, Mouse Monoclonal Antibody.

3-fucosyl-N-acetyllactosamine (3-FAL) or CD15 or X-hapten plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on >95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. CD15 is also expressed in Reed-Sternberg cells and some epithelial cells. CD15 antibody is very useful in the identification of Hodgkin's disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance.

Host Species: Mouse

Clone: MMA; same as LeuM1

Isotype: IgM/κ

Species Reactivity: Human. Others not tested.

Epitope: Not determined

Immunogen: U937 histiocytic cell line

Molecular Weight: 220kDa

Positive Control: Reed-Sternberg's cells in Hodgkin's lymphoma

Cellular Localization: Membrane and granular paranuclear

Recommended for:

  • Immunohistochemistry (Formalin/paraffin)
  • Flow Cytometry