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CD144 (VE-Cadherin) Rat anti-Mouse, eFluor 660, Clone: eBioBV13 (BV13), eBioscience™

Rat Monoclonal Antibody

$239.25 - $558.25

Specifications

Antigen CD144 (VE-Cadherin)
Clone eBioBV13 (BV13)
Host Species Rat
Gene Alias Cdh5, Cadherin 5, Vascular endothelial cadherin
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501124304

 
affymetrix
50144180
25μg Each for $239.25

501124305

 
affymetrix
50144182
100μg Each for $558.25
Description & Specifications

Specifications

Antigen CD144 (VE-Cadherin)
Clone eBioBV13 (BV13)
Host Species Rat
Gene Alias Cdh5, Cadherin 5, Vascular endothelial cadherin
Species Reactivity Mouse
Applications Flow Cytometry
Regulatory Status RUO
Conjugate eFluor 660
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.2mg/mL

The eBioBV13 (BV13) monoclonal antibody reacts with mouse VE-Cadherin (CD144). VE-Cadherin is a 120kDa member of the type II Cadherin family, characterized by the presence of 5 extracellular cadherin domains (ECD), and anchored to the actin cytoskeleton through their cytoplasmic tail. VE-Cadherin mediates homophilic adhesion between neighbouring endothelial cells and is localized within specialized structures at cell-cell contacts, called adherens junctions. VE-Cadherin is expressed constitutively throughout the entire vasculature, and is required for numerous endothelial cell functions including migration, survival, contact-dependent growth inhibition and endothelial cell assembly into tubular structures. Furthermore, it is thought that VE-Cadherin+CD45- cells from the yolk sac or aorta-gonad-mesonephros (AGM) have the potential to give rise to hematopoietic cells.