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CD144 (VE-Cadherin) Rat anti-Mouse, Clone: eBioBV14 (BV14), eBioscience™

Rat Monoclonal Antibody

$196.68 - $328.68

Specifications

Antigen CD144 (VE-Cadherin)
Clone eBioBV14 (BV14)
Host Species Rat
Gene Alias Cadherin 5
Applications Functional Assay,Immunohistochemistry (Frozen),Immunoprecipitation,Western Blot
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5012893 Life Technologies
LS14144282
100μg Each for $196.68
5012894 Life Technologies
LS14144285
500μg Each for $328.68
Specifications

Description

The BV14 monoclonal antibody reacts with mouse VE-Cadherin (CD144). VE-Cadherin is a 120kDa member of the type II Cadherin family, characterized by the presence of 5 extracellular cadherin domains (ECD), and anchored to the actin cytoskeleton through their cytoplasmic tail. VE-Cadherin mediates homophilic adhesion between neighbouring endothelial cells and is localized within specialized structures at cell-cell contacts, called adherens junctions. VE-Cadherin is expressed constitutively throughout the entire vasculature, and is required for numerous endothelial cell functions including migration, survival, contact-dependent growth inhibition and endothelial cell assembly into tubular structures. Furthermore, it is thought that VE-Cadherin+CD45- cells from the yolk sac or aorta-gonad-mesonephros (AGM)+ have the potential to give rise to hematopoietic cells. Cross-blocking experiments suggest that BV14 recognizes a different epitope than another mouse VE-Cadherin monoclonal antibody, BV13.
Description & Specifications

Specifications

CD144 (VE-Cadherin)
Rat
Functional Assay,Immunohistochemistry (Frozen),Immunoprecipitation,Western Blot
Unlabeled
Store at 2-8°C.
Monoclonal
0.5mg/mL
eBioBV14 (BV14)
Cadherin 5
RUO
Purified
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer