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CD144 (VE-Cadherin) Rat anti-Mouse, Clone: eBioBV13 (BV13), Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

$143.55 - $506.05

Specifications

Antigen CD144 (VE-Cadherin)
Clone eBioBV13 (BV13)
Host Species Rat
Gene Alias Cdh5, Cadherin-5, Vascular endothelial cadherin
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5014465

 
affymetrix
16144181
50μg Each for $143.55

5014466

 
affymetrix
16-1441-82
100μg Each for $274.05

5014467

 
affymetrix
16144185
500μg Each for $506.05
Description & Specifications

Specifications

Antigen CD144 (VE-Cadherin)
Clone eBioBV13 (BV13)
Host Species Rat
Gene Alias Cdh5, Cadherin-5, Vascular endothelial cadherin
Species Reactivity Mouse
Applications Flow Cytometry
Applications Functional Assay
Applications Immunohistochemistry (Frozen)
Applications Immunoprecipitation
Applications Western Blotting
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, no sodium azide
Concentration 1mg/mL

The BV13 monoclonal antibody reacts with mouse VE-Cadherin (CD144). VE-Cadherin is a 120kDa member of the type II Cadherin family, characterized by the presence of 5 extracellular cadherin domains (ECD), and anchored to the actin cytoskeleton through their cytoplasmic tail. VE-Cadherin mediates homophilic adhesion between neighbouring endothelial cells and is localized within specialized structures at cell-cell contacts, called adherens junctions. VE-Cadherin is expressed constitutively throughout the entire vasculature, and is required for numerous endothelial cell functions including migration, survival, contact-dependent growth inhibition and endothelial cell assembly into tubular structures. Furthermore, it is thought that VE-Cadherin+CD45- cells from the yolk sac or aorta-gonad-mesonephros (AGM) have the potential to give rise to hematopoietic cells.