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CD144 (VE-Cadherin) Rat anti-Mouse, Alexa Fluor 488, Clone: BV13, eBioscience™

Rat Monoclonal Antibody

$288.55 - $535.05

Specifications

Antigen CD144 (VE-Cadherin)
Clone eBioBV13 (BV13)
Host Species Rat
Gene Alias Cdh5, Cadherin-5, Vascular endothelial cadherin
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5016729

 
affymetrix
53144180
25μg Each for $288.55

5016730

 
affymetrix
53144182
100μg Each for $535.05
Description & Specifications

Specifications

Antigen CD144 (VE-Cadherin)
Clone eBioBV13 (BV13)
Host Species Rat
Gene Alias Cdh5, Cadherin-5, Vascular endothelial cadherin
Species Reactivity Mouse
Applications Flow Cytometry
Applications Immunohistochemistry (Frozen)
Regulatory Status RUO
Conjugate Alexa Fluor 488
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.5mg/mL

The BV13 monoclonal antibody reacts with mouse VE-Cadherin (CD144). VE-Cadherin is a 120kDa member of the type II Cadherin family, characterized by the presence of 5 extracellular cadherin domains (ECD), and anchored to the actin cytoskeleton through their cytoplasmic tail. VE-Cadherin mediates homophilic adhesion between neighbouring endothelial cells and is localized within specialized structures at cell-cell contacts, called adherens junctions. VE-Cadherin is expressed constitutively throughout the entire vasculature, and is required for numerous endothelial cell functions including migration, survival, contact-dependent growth inhibition and endothelial cell assembly into tubular structures. Furthermore, it is thought that VE-Cadherin+CD45- cells from the yolk sac or aorta-gonad-mesonephros (AGM) have the potential to give rise to hematopoietic cells.