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CD142 Mouse anti-Human, Clone: HTF-1, Functional Grade, eBioscience™

Mouse Monoclonal Antibody, Functional Grade

$201.55 - $506.05

Specifications

Antigen CD142
Clone HTF-1
Host Species Mouse
Gene Alias Tissue Factor
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501122948

 
affymetrix
16142982
100μg Each for $201.55

501122949

 
affymetrix
16142985
500μg Each for $506.05
Description & Specifications

Specifications

Antigen CD142
Clone HTF-1
Host Species Mouse
Gene Alias Tissue Factor
Species Reactivity Human
Applications Flow Cytometry
Applications Functional Assay
Applications Immunocytochemistry
Applications Western Blotting
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, no sodium azide
Concentration 1mg/mL

This HTF-1 monoclonal antibody reacts with human CD142, which is also known as Tissue Factor. Expression of this type I transmembrane glycoprotein on endothelial cells, monocytes, macrophages, and platelets can be induced by inflammatory mediators (e.g., LPS, IL-1b, TNFa, PMA, or endotoxin). On the other hand, CD142 is expressed constitutively by some tumor cells (e.g., lung, pancreatic, breast, and colon) and non-immune tissues such as the vasculature, central nervous system, kidney, epithelia, and placenta. Studies have also suggested that CD142 exists as a soluble form that circulates in blood. CD142 initiates blood coagulation by associating with and activating the circulating factors VII and VIIa.

The HTF-1 antibody has been reported to exhibit blocking activity.