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CD137 (4-1BB) Golden Syrian Hamster anti-Mouse, PE, Clone: 17B5, eBioscience™

Golden Syrian Hamster Monoclonal Antibody

$143.55 - $419.05

Specifications

Antigen CD137 (4-1BB)
Clone 17B5
Host Species Golden Syrian Hamster
Gene Alias Ly-63, TNFRSF9, ILA
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5010624

 
affymetrix
12137181
50μg Each for $143.55

5010625

 
affymetrix
12137182
100μg Each for $274.05

5010626

 
affymetrix
12137183
200μg Each for $419.05
Description & Specifications

Specifications

Antigen CD137 (4-1BB)
Clone 17B5
Host Species Golden Syrian Hamster
Gene Alias Ly-63, TNFRSF9, ILA
Species Reactivity Mouse
Applications Flow Cytometry
Regulatory Status RUO
Conjugate PE
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.2mg/mL

The 17B5 monoclonal antibody reacts with mouse CD137, also known as 4-1BB, a member of the TNFR superfamily. CD137 is expressed as monomers, dimers, and tetramers on the surface of activated T cells around day 4-6 after activation through the TCR complex. Interaction of CD137 with its ligand, 4-1BBL, is reported to deliver a costimulatory signal important in the T-APC interaction. Recent data suggests CD317 is expressed on Tregs and may play a role in their proliferation. The monoclonal antibody 17B5 has strong antagonistic effect in in vitro functional assays.