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CD127 Rat anti-Mouse, PE-Cy5, Clone: A7R34, eBioscience™

Rat Monoclonal Antibody

$201.55 - $477.05

Specifications

Antigen CD127
Clone A7R34
Host Species Rat
Gene Alias Interleukin-7 Receptor alpha
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5014096

 
affymetrix
15127181
50μg Each for $201.55

5014097

 
affymetrix
15-1271-82
100μg Each for $404.55

5014098

 
affymetrix
15127183
200μg Each for $477.05
Description & Specifications

Specifications

Antigen CD127
Clone A7R34
Host Species Rat
Gene Alias Interleukin-7 Receptor alpha
Species Reactivity Mouse
Applications Flow Cytometry
Regulatory Status RUO
Conjugate PE-Cy5
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.2mg/mL

The A7R34 monoclonal antibody reacts with mouse CD127, the high affinity alpha subunit of the mouse IL-7 receptor. IL-7 receptor alpha chain is expressed by immature B cells in the bone marrow, double-negative (CD4-CD8-), single-positive (CD4+ and CD8+), but not double-positive (CD4+CD8+) thymocytes. In the periphery, mature T cells express CD127 at low level. A7R34 inhibits binding of IL-7 to its receptor and has been used in in vivo and in vitro studies to elucidate the role of IL-7 in T and B cell development and activation. Binding of A7R34 blocks the binding of SB/199, another antibody which recognizes mouse CD127.