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CD11c Mouse, APC-eFluor 780, Clone: BU15, eBioscience™

Mouse Monoclonal Antibody

$246.50 - $519.10

Specifications

Antigen CD11c
Clone BU15
Host Species Mouse
Gene Alias Integrin alpha-X, p150, CR4, Integrin aX, ITGAX
Species Reactivity Canine, Cynomolgus, Human, Non-human primate
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 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501124010

 
affymetrix
47012842
100 tests Each for $519.10

501129279

 
affymetrix
47-0128-41
25 tests Each for $246.50
Description & Specifications

Specifications

Antigen CD11c
Clone BU15
Host Species Mouse
Gene Alias Integrin alpha-X, p150, CR4, Integrin aX, ITGAX
Species Reactivity Canine, Cynomolgus, Human, Non-human primate
Applications Flow Cytometry
Regulatory Status RUO
Conjugate APC-eFluor 780
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material. This tandem dye is sensitive to photo-induced oxidation. Protect this vial from light during storage
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.125μg)/test

The BU15 monoclonal antibody reacts with canine, human, and non-human primate CD11c, the 150kDa integrin aX chain. CD11c non-covalently associates with beta2 integrin to form the CD11c/CD18 heterodimer. This complex is expressed on monocytes, granulocytes, macrophages, NK, dendritic cells, and subset of T and B lymphocytes. CD11c/CD18 binds to CD54, iC3b and fibrinogen and plays a role in leukocyte adhesive interactions. CD11c also binds complement fragment iC3b to mediate phagocytosis of opsonized particles.

The BU15 antibody has been reported to crossreact to cynomologus monkey. Moreover, this antibody has been reported to exhibit blocking activity. Crossblocking studies suggest that BU15 recognizes a different epitope from clone 3.9.