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CD11c Mouse anti-Human, Biotin, Clone: 118/A5, eBioscience™

Mouse Monoclonal Antibody

$117.45 - $213.84

Specifications

Antigen CD11c
Clone 118/A5
Host Species Murine
Gene Alias Integrin alpha X
Applications Immunohistochemistry (Formalin/Paraffin),Immunohistochemistry (Frozen),Microscopy
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501122600 Life Technologies
LS13976180
25μg Each for $117.45
501122601 Life Technologies
LS13976182
100μg Each for $213.84
Specifications

Description

The monoclonal antibody 118/A5 recognizes human CD11c, a 150 kD type I transmembrane protein which is also known as integrin alpha X. Integrins are heterodimeric integral membrane proteins made up of an alpha and a beta chain and are involved in cell adhesion. The CD11/CD18 adhesion molecules consist of three heterodimers sharing a common beta subunit (CD18) with a distinct alpha subunit (CD11a, CD11b, CD11c). The CD11c/CD18 complex is expressed on dendritic cells (highly expressed on type 1 myeloid DCs), monocytes, macrophages, granulocytes, NK cells, and subsets of T and B cells. CD11c is also expressed in hairy cell leukemias, acute nonlymphocytic leukemias, and some B-cell chronic lymphocytic leukemias. CD11c plays a role in adhesion and CTL killing through its interactions with CD54, iC3b and fibrinogen.
Description & Specifications

Specifications

CD11c
Murine
Immunohistochemistry (Formalin/Paraffin),Immunohistochemistry (Frozen),Microscopy
Biotin
Store at 2-8°C. Do not freeze.
Monoclonal
0.5mg/mL
118/A5
Integrin alpha X
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer