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CD11b Rat anti-Mouse, Clone: M1/70, Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

$216.05 - $651.05

Specifications

Antigen CD11b
Clone M1/70
Host Species Rat
Gene Alias Integrin alpha M, ITGAM, Mac-1 alpha (Mac1A), Complement Receptor 3 alpha (CR3A)
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501122937

 
affymetrix
16011282
100μg Each for $216.05

5014227

 
affymetrix
16011286
1mg Each for $651.05

5014226

 
affymetrix
16011285
500μg Each for $390.05
Description & Specifications

Specifications

Antigen CD11b
Clone M1/70
Host Species Rat
Gene Alias Integrin alpha M, ITGAM, Mac-1 alpha (Mac1A), Complement Receptor 3 alpha (CR3A)
Species Reactivity Mouse
Applications Flow Cytometry
Applications Functional Assay
Applications Immunohistochemistry (Frozen)
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, no sodium azide

The M1/70 monoclonal antibody reacts with mouse CD11b, the 165-170kDa integrin αM. CD11b non-covalently associates with CD18 to form αMβ2 integrin (Mac-1) and binds to CD54 (ICAM-1), C3bi, and fibrinogen. Mac-1 is expressed by macrophages, NK cells, granulocytes, activated lymphocytes and mouse B-1 cells in the peritoneal cavity. M1/70 is also cross-reactive to human CD11b, and can be used for the detection of this antigen on human peripheral blood monocytes, granulocytes, and a subset of NK cells. Through interactions with its ligands, CD11b participates in adhesive cell interactions.