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CD117 (c-kit) Mouse anti-Human, PE, Clone: YB5.B8, eBioscience™

Mouse Monoclonal Antibody

$158.05 - $332.05

Specifications

Antigen CD117 (c-kit)
Clone YB5.B8
Host Species Mouse
Gene Alias cKit, Mast/Stem Cell Growth Factor Receptor
Species Reactivity Human
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5010578

 
affymetrix
12117941
25 tests Each for $158.05

5010579

 
affymetrix
12117942
100 tests Each for $332.05
Description & Specifications

Specifications

Antigen CD117 (c-kit)
Clone YB5.B8
Host Species Mouse
Gene Alias cKit, Mast/Stem Cell Growth Factor Receptor
Species Reactivity Human
Applications Flow Cytometry
Regulatory Status RUO
Conjugate PE
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 5μL (0.25μg)/test

The YB5.B8 monoclonal antibody reacts with human CD117, also known as c-Kit, Steel factor receptor and stem cell factor receptor. A member of the tyrosine kinase receptor family, this 145kDa molecule is expressed by hematopoietic progenitor cell subsets and mast cells. The interaction of c-Kit and Steel factor promotes proliferation and differentiation of hematopoietic progenitor cells and mast cell differentiation. CD117 is also expressed by melanocytes and plays a role in signaling and activation of these cells.

When interested in staining HSCs from peripheral blood, we recommend the use of clone 104D2. Please refer to cat. 17-1178.