missing translation for 'onlineSavingsMsg'
Learn More
Please login to your online account to display your discounted pricing

CD115 (c-fms) Rat anti-Human, PE, Clone: 12-3A3-1B10, eBioscience™

Rat Monoclonal Antibody

$187.05 - $448.05

Specifications

Antigen CD115 (c-fms)
Clone 12-3A3-1B10
Host Species Rat
Gene Alias CSF1R, colony-stimulating factor 1 Receptor
Species Reactivity Human
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
5010565 Life Technologies
LS12115941
25 Tests Each for $187.05
5010566 Life Technologies
LS12115942
100 Tests Each for $448.05
Specifications

Description

CD115 or Colony-Stimulating Factor-1 Receptor (CSF-1R) is expressed on cells committed to the monocyte lineage and osteoclasts. CSF-1R is a disulfide-linked homodimer, which upon binding of its ligand, CSF-1, undergoes tyrosine autophosphorylation and subsequently, phosphorylates other membrane-proximal downstream targets which results in cytoskeletal remodeling, gene transcription and protein translation. CSF-1R activation promotes the survival, proliferation and differentiation of mononuclear phagocytes and the spreading and motility of macrophages. In osteoclasts, CSF-1R synergizes with RANKL to regulate the differentiation of mononuclear phagocytes to osteoclasts.
Description & Specifications

Specifications

CD115 (c-fms)
Rat
Human
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
12-3A3-1B10
CSF1R, colony-stimulating factor 1 Receptor
Flow Cytometry
PE
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
5μL (0.03μg)/test