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CD106 (VCAM-1) Rat anti-Mouse, eFluor 660, Clone: 429, eBioscience™

Rat Monoclonal Antibody

$125.40 - $283.80

Specifications

Antigen CD106 (VCAM-1)
Clone 429
Host Species Rat
Gene Alias VCAM1, vascular cell adhesion molecule-1
Applications Flow Cytometry
View More Specs

Disclaimers:

For Research Use Only.



Products ${productFamilyLength}
Catalog Number Mfr. No. Quantity Price Quantity  
Catalog Number Mfr. No. Quantity Price Quantity  
501124292 Life Technologies
LS50106180
25μg Each for $125.40
501124293 Life Technologies
LS50106182
100μg Each for $283.80
Specifications

Description

The 429 monoclonal antibody reacts with mouse CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1), a 110kDa transmembrane glycoprotein expressed by myeloid lineage and bone marrow stromal cells. Endothelial cells constitutively express low levels of CD106 and upregulate it upon cytokine stimulation. CD106 binds to integrin alpha4 beta1 (VLA-4, CD49d/CD29) and Integrin a4b7 (LPAM-1) and these interactions in the bone marrow and thymus are important for early lymphocyte and myeloid development. Cytokine-mediated upregulation of CD106 on endothelial cells suggests a role for this antigen in the inflammatory response.
Description & Specifications

Specifications

CD106 (VCAM-1)
Rat
Flow Cytometry
eFluor 660
Store at 2-8°C. Do not freeze. Light-sensitive material.
Monoclonal
0.2mg/mL
429
VCAM1, vascular cell adhesion molecule-1
RUO
Conjugated
Primary
aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer