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CD106 (VCAM-1) Rat anti-Mouse, eFluor 450, Clone: 429, eBioscience™

Rat Monoclonal Antibody

$201.55 - $404.55

Specifications

Antigen CD106 (VCAM-1)
Clone 429
Host Species Rat
Gene Alias VCAM1, vascular cell adhesion molecule-1
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

501124132

 
affymetrix
48106180
25μg Each for $201.55

5016323

 
affymetrix
48106182
100μg Each for $404.55
Description & Specifications

Specifications

Antigen CD106 (VCAM-1)
Clone 429
Host Species Rat
Gene Alias VCAM1, vascular cell adhesion molecule-1
Species Reactivity Mouse
Applications Flow Cytometry
Regulatory Status RUO
Conjugate eFluor 450
Format Conjugated
Storage Requirements Store at 2-8°C. Do not freeze. Light-sensitive material.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, 0.09% sodium azide, may contain carrier protein/stabilizer
Concentration 0.2mg/mL

The 429 monoclonal antibody reacts with mouse CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1), a 110kDa transmembrane glycoprotein expressed by myeloid lineage and bone marrow stromal cells. Endothelial cells constitutively express low levels of CD106 and upregulate it upon cytokine stimulation. CD106 binds to integrin α4β1 (VLA-4, CD49d/CD29) and Integrin a4b7 (LPAM-1) and these interactions in the bone marrow and thymus are important for early lymphocyte and myeloid development. Cytokine-mediated upregulation of CD106 on endothelial cells suggests a role for this antigen in the inflammatory response.