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CD106 (VCAM-1) Rat anti-Mouse, Clone: 429, Functional Grade, eBioscience™

Rat Monoclonal Antibody, Functional Grade

$114.55 - $433.55

Specifications

Antigen CD106 (VCAM-1)
Clone 429
Host Species Rat
Gene Alias VCAM1, vascular cell adhesion molecule-1
Species Reactivity Mouse
View More Specs

 Disclaimers

For Research Use Only.

Products
Catalog Number Mfr. No. Quantity Price Quantity    

5014430

 
affymetrix
16-1061-82
100μg Each for $230.55

5014429

 
affymetrix
16106181
50μg Each for $114.55

5014431

 
affymetrix
16-1061-85
500μg Each for $433.55
Description & Specifications

Specifications

Antigen CD106 (VCAM-1)
Clone 429
Host Species Rat
Gene Alias VCAM1, vascular cell adhesion molecule-1
Species Reactivity Mouse
Applications Flow Cytometry
Applications Functional Assay
Regulatory Status RUO
Conjugate Unlabeled
Format Purified
Storage Requirements Store at 2-8°C.
Primary or Secondary Primary
Monoclonal or Polyclonal Monoclonal
Formulation aqueous buffer, no sodium azide
Concentration 1mg/mL

The 429 monoclonal antibody reacts with mouse CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1), a 110kDa transmembrane glycoprotein expressed by myeloid lineage and bone marrow stromal cells. Endothelial cells constitutively express low levels of CD106 and upregulate it upon cytokine stimulation. CD106 binds to integrin α4β1 (VLA-4, CD49d/CD29) and Integrin a4b7 (LPAM-1) and these interactions in the bone marrow and thymus are important for early lymphocyte and myeloid development. Cytokine-mediated upregulation of CD106 on endothelial cells suggests a role for this antigen in the inflammatory response.